To date, we are not aware of any studies elucidating the impact of preprocedural glycemic control on periprocedural myocardial injury or infarction in patients with type 2 DM who underwent elective PCI. Thus, the aim of this study was to characterize the relation between HbA1c and periprocedural myocardial injury or infarction in patients with type 2 DM undergoing elective PCI. Between December 2010 and December 2012, 1032 consecutive diabetic patients with normal levels of cardiac troponin I and creatine kinase-MB and without acute myocardial PRT4165 infarction in the past 4 weeks who attempt to undergo elective PCI at our center were eligible for this study. Of these patients, 33 patients were excluded because a total or subtotal chronic occlusion could not be crossed with a wire, 2 patients were excluded because a severely calcified or tortuous lesion could not be crossed with a balloon, 3 patients were excluded because treated with atheroablative, distal protection devices or aspiration thrombectomy. None of the patients died in the hospital. Thus, 994 patients were effectively included in the present study. Adult patients with type 2 diabetes were identified based on recorded type 2 diabetes diagnosis or a prescription for oral hypoglycemic medication or insulin. Angiographic success of PCI was defined as residual stenosis less than 20% with stenting and residual stenosis Camalexin with balloon angioplasty only by visual estimation. Procedural characteristics according to quartiles of HbA1c were shown in Table 2. Patients with higher HbA1c levels were more likely to receive more postdilatation. There were no significant differences in vascular access, target vessel, target lesion site and target lesion type among quartiles of HbA1c. There were also no significant differences in number of stents, total stent length, predilation times, maximum inflation pressure and maximum inflation time among quartiles of HbA1c. There was a similar trend that lower preprocedural HbA1c and fasting glucose levels were associated with higher postprocedural cTnI levels in the simple regression analysis.